2DPI
Ternary complex of hPoli with DNA and dCTP
Summary for 2DPI
Entry DOI | 10.2210/pdb2dpi/pdb |
Related | 1T3N 2ALZ 2DPJ |
Descriptor | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... (6 entities in total) |
Functional Keywords | dna dependent dna polymerase, ethenoda adduct, lesion bypass, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 52405.35 |
Authors | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2006-05-12, release date: 2006-07-04, Last modification date: 2023-10-25) |
Primary citation | Nair, D.T.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat.Struct.Mol.Biol., 13:619-625, 2006 Cited by PubMed: 16819516DOI: 10.1038/nsmb1118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report