2DO2
Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution
Summary for 2DO2
Entry DOI | 10.2210/pdb2do2/pdb |
Related | 1Q6V |
Descriptor | Phospholipase A2 VRV-PL-VIIIa, Ala-Leu-Ala-Ser-Lys, SULFATE ION, ... (4 entities in total) |
Functional Keywords | cys 49 phospholipase a2, synthetic pentapeptide, complex, hydrolase |
Biological source | Daboia russellii pulchella More |
Cellular location | Secreted: P59071 |
Total number of polymer chains | 2 |
Total formula weight | 14078.30 |
Authors | Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. (deposition date: 2006-04-27, release date: 2006-05-16, Last modification date: 2023-10-25) |
Primary citation | Singh, N.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Singh, T.P. Design of specific inhibitors of phospholipase A2: Crystal structure of the complex formed between a group II Cys 49 phospholipase A2 and a designed pentapeptide Ala-Leu-Ala-Ser-Lys at 2.6A resolution To be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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