2DHN

COMPLEX OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS WITH 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 2.2 A RESOLUTION

Summary for 2DHN

Entry DOI	10.2210/pdb2dhn/pdb
Descriptor	7,8-DIHYDRONEOPTERIN ALDOLASE, 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE (3 entities in total)
Functional Keywords	product complex, pterine binding, folate biosynthesis, antibiotic target, beta-barrel
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	13964.81
Authors	Hennig, M.,D'Arcy, A.,Hampele, I.C.,Page, M.G.P.,Oefner, C.H.,Dale, G. (deposition date: 1998-03-31, release date: 1999-04-20, Last modification date: 2024-04-03)
Primary citation	Hennig, M.,D'Arcy, A.,Hampele, I.C.,Page, M.G.,Oefner, C.,Dale, G.E. Crystal structure and reaction mechanism of 7,8-dihydroneopterin aldolase from Staphylococcus aureus. Nat.Struct.Biol., 5:357-362, 1998 Cited by PubMed: 9586996 DOI: 10.1038/nsb0598-357 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation