2DDK

Crystal structure of human myo-inositol monophosphatase 2 (IMPA2) (orthorhombic form)

Summary for 2DDK

• Entry DOI: 10.2210/pdb2ddk/pdb
• Related: 2CZH 2CZI 2CZK
• Descriptor: Inositol monophosphatase 2 (2 entities in total)
• Functional Keywords: myo-inositol monophosphatase (impa), bipolar disorder, schizophrenia, febrile seizures, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 64804.03

Authors

Arai, R.,Ito, K.,Kamo-Uchikubo, T.,Bessho, Y.,Ohba, H.,Ohnishi, T.,Yoshikawa, T.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2006-01-30, release date: 2007-02-06, Last modification date: 2023-10-25)

• Primary citation: Arai, R.,Ito, K.,Ohnishi, T.,Ohba, H.,Akasaka, R.,Bessho, Y.,Hanawa-Suetsugu, K.,Yoshikawa, T.,Shirouzu, M.,Yokoyama, S.; Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures; Proteins, 67:732-742, 2007; PubMed: 17340635; DOI: 10.1002/prot.21299

Experimental method

X-RAY DIFFRACTION (2.7 Å)