2D4V

Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans

Summary for 2D4V

Descriptorisocitrate dehydrogenase, CITRATE ANION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
Functional Keywordsalpha and beta protein, isocitrate/isopropylmalate dehydrogenase-like fold, oxidoreductase
Biological sourceAcidithiobacillus thiooxidans
Total number of polymer chains4
Total molecular weight188481.24
Authors
Imada, K.,Tamura, T.,Namba, K.,Inagaki, K. (deposition date: 2005-10-24, release date: 2006-11-14, Last modification date: 2011-07-13)
Primary citation
Imada, K.,Tamura, T.,Takenaka, R.,Kobayashi, I.,Namba, K.,Inagaki, K.
Structure and quantum chemical analysis of NAD+-dependent isocitrate dehydrogenase: hydride transfer and co-factor specificity
Proteins, 70:63-71, 2008
PubMed: 17634983 (PDB entries with the same primary citation)
DOI: 10.1002/prot.21486
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20760.1%1.9%2.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2d4v
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Molmil generated image of 2d4v
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Molmil generated image of 2d4v
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More Biological unit images

Molmil generated image of 2d4v
no rotation
Molmil generated image of 2d4v
rotated about x axis by 90°
Molmil generated image of 2d4v
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2d4v.pdb1.gz [146.36 KB])
Coordinate files for Biological unit (2d4v.pdb2.gz [149.69 KB])