2D2X

Crystal structure of 2-deoxy-scyllo-inosose synthase

Summary for 2D2X

Entry DOI	10.2210/pdb2d2x/pdb
Descriptor	2-deoxy-scyllo-inosose synthase, COBALT (II) ION, SULFITE ION, ... (5 entities in total)
Functional Keywords	aminoglycoside, 2-deoxystreptamine, dehydroquinate synthase, lyase
Biological source	Bacillus circulans
Total number of polymer chains	2
Total formula weight	82257.78
Authors	Nango, E.,Kumasaka, T.,Tanaka, N.,Kakinuma, K.,Eguchi, T. (deposition date: 2005-09-20, release date: 2006-10-03, Last modification date: 2011-07-13)
Primary citation	Nango, E.,Kumasaka, T.,Hirayama, T.,Tanaka, N.,Eguchi, T. Structure of 2-deoxy-scyllo-inosose synthase, a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics, in complex with a mechanism-based inhibitor and NAD+ Proteins, 70:517-527, 2008 Cited by PubMed: 17879343 DOI: 10.1002/prot.21526 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation