2D06

Human Sult1A1 Complexed With Pap and estradiol

Summary for 2D06

• Entry DOI: 10.2210/pdb2d06/pdb
• Descriptor: Sulfotransferase 1A1, ADENOSINE-3'-5'-DIPHOSPHATE, ESTRADIOL, ... (4 entities in total)
• Functional Keywords: sult 1a1, pap, estradiol, substrarte inhibition, dead end complex, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P50225
• Total number of polymer chains: 2
• Total formula weight: 69839.78

Authors

Gamage, N.U.,Tsvetanov, S.,Duggleby, R.G.,McManus, M.E.,Martin, J.L. (deposition date: 2005-07-25, release date: 2005-10-25, Last modification date: 2023-10-25)

• Primary citation: Gamage, N.U.,Tsvetanov, S.,Duggleby, R.G.,McManus, M.E.,Martin, J.L.; The structure of human SULT1A1 crystallized with estradiol. An insight into active site plasticity and substrate inhibition with multi-ring substrates; J.Biol.Chem., 280:41482-41486, 2005; PubMed: 16221673; DOI: 10.1074/jbc.M508289200

Experimental method

X-RAY DIFFRACTION (2.3 Å)