2CVD
Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79
Summary for 2CVD
| Entry DOI | 10.2210/pdb2cvd/pdb |
| Related | 1IYH 1IYI |
| Descriptor | Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, GLUTATHIONE, ... (6 entities in total) |
| Functional Keywords | glutathione-s-transferase, isomerase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: O60760 |
| Total number of polymer chains | 4 |
| Total formula weight | 96459.41 |
| Authors | Aritake, K.,Kado, Y.,Inoue, T.,Miyano, M.,Urade, Y. (deposition date: 2005-06-02, release date: 2006-04-18, Last modification date: 2023-10-25) |
| Primary citation | Aritake, K.,Kado, Y.,Inoue, T.,Miyano, M.,Urade, Y. Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D Synthase. J.Biol.Chem., 281:15277-15286, 2006 Cited by PubMed: 16547010DOI: 10.1074/jbc.M506431200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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