2CVD
Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79
Summary for 2CVD
Entry DOI | 10.2210/pdb2cvd/pdb |
Related | 1IYH 1IYI |
Descriptor | Glutathione-requiring prostaglandin D synthase, MAGNESIUM ION, GLUTATHIONE, ... (6 entities in total) |
Functional Keywords | glutathione-s-transferase, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O60760 |
Total number of polymer chains | 4 |
Total formula weight | 96459.41 |
Authors | Aritake, K.,Kado, Y.,Inoue, T.,Miyano, M.,Urade, Y. (deposition date: 2005-06-02, release date: 2006-04-18, Last modification date: 2023-10-25) |
Primary citation | Aritake, K.,Kado, Y.,Inoue, T.,Miyano, M.,Urade, Y. Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D Synthase. J.Biol.Chem., 281:15277-15286, 2006 Cited by PubMed: 16547010DOI: 10.1074/jbc.M506431200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
Download full validation report