2CNQ

Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with ADP, AICAR, succinate

Summary for 2CNQ

• Entry DOI: 10.2210/pdb2cnq/pdb
• Related: 1A48 1KUT 1OBD 1OBG 2CNU 2CNV 2GQR 2GQS
• Descriptor: PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, ADENOSINE-5'-DIPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (8 entities in total)
• Functional Keywords: ligase, phosphoribosylaminoimidazolesuccinocarboxamide (saicar) syn ligase, synthetase, acetylation, atp-binding protein, purine biosynthesis
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• Total number of polymer chains: 1
• Total formula weight: 37068.02

Authors

Urusova, D.V.,Antonyuk, S.V.,Grebenko, A.I.,Levdikov, V.M.,Barynin, V.V.,Popov, A.N.,Lamzin, V.S.,Melik-Adamyan, W.R. (deposition date: 2006-05-23, release date: 2006-06-08, Last modification date: 2023-12-13)

• Primary citation: Urusova, D.V.,Antonyuk, S.V.,Grebenko, A.I.,Levdikov, V.M.,Barynin, V.V.,Popov, A.N.,Lamzin, V.S.,Melik-Adamyan, W.R.; Saicar Synthase: Substrate Recognition, Conformational Flexibility and Catalysis.; To be Published,

Experimental method

X-RAY DIFFRACTION (1 Å)