2CNQ

Atomic resolution structure of SAICAR-synthase from Saccharomyces cerevisiae complexed with ADP, AICAR, succinate

2CNQ の概要

• エントリーDOI: 10.2210/pdb2cnq/pdb
• 関連するPDBエントリー: 1A48 1KUT 1OBD 1OBG 2CNU 2CNV 2GQR 2GQS
• 分子名称: PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE, ADENOSINE-5'-DIPHOSPHATE, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (8 entities in total)
• 機能のキーワード: ligase, phosphoribosylaminoimidazolesuccinocarboxamide (saicar) syn ligase, synthetase, acetylation, atp-binding protein, purine biosynthesis
• 由来する生物種: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37068.02

構造登録者

Urusova, D.V.,Antonyuk, S.V.,Grebenko, A.I.,Levdikov, V.M.,Barynin, V.V.,Popov, A.N.,Lamzin, V.S.,Melik-Adamyan, W.R. (登録日: 2006-05-23, 公開日: 2006-06-08, 最終更新日: 2023-12-13)

• 主引用文献: Urusova, D.V.,Antonyuk, S.V.,Grebenko, A.I.,Levdikov, V.M.,Barynin, V.V.,Popov, A.N.,Lamzin, V.S.,Melik-Adamyan, W.R.; Saicar Synthase: Substrate Recognition, Conformational Flexibility and Catalysis.; To be Published,

実験手法

X-RAY DIFFRACTION (1 Å)