2CML

Structure of Neuraminidase from English Duck Subtype N6 Complexed with 30 MM ZANAMIVIR, Crystal Soaked for 3 Hours at 291 K.

Summary for 2CML

• Entry DOI: 10.2210/pdb2cml/pdb
• Related: 1V0Z 1W1X 1W20 1W21
• Descriptor: NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, ... (10 entities in total)
• Functional Keywords: hb site, hydrolase, subtype n6, glycosidase, influenza type a, sialic acid, neuraminidase, transmembrane
• Biological source: INFLUENZA A VIRUS
• Total number of polymer chains: 4
• Total formula weight: 181968.38

Authors

Rudino-Pinera, E.,Tunnah, P.,Lukacik, P.,Crennell, S.J.,Webster, R.G.,Laver, W.G.,Garman, E.F. (deposition date: 2006-05-10, release date: 2007-06-05, Last modification date: 2023-12-13)

• Primary citation: Rudino-Pinera, E.,Tunnah, P.,Crennell, S.J.,Webster, R.G.,Laver, W.G.,Garman, E.F.; The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites; To be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)