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2CJF

TYPE II DEHYDROQUINASE INHIBITOR COMPLEX

Summary for 2CJF
Entry DOI10.2210/pdb2cjf/pdb
Related1D0I 1GTZ 1GU0 1GU1 1V1J 2BT4
Descriptor3-DEHYDROQUINATE DEHYDRATASE, (1S,4S,5S)-1,4,5-TRIHYDROXY-3-[3-(PHENYLTHIO)PHENYL]CYCLOHEX-2-ENE-1-CARBOXYLIC ACID, GLYCEROL, ... (6 entities in total)
Functional Keywordsdehydroquinase, shikimate pathway, dehydroquinate, drug design, lyase, amino-acid biosynthesis, aromatic amino acid biosynthesis
Biological sourceSTREPTOMYCES COELICOLOR
Total number of polymer chains12
Total formula weight206684.09
Authors
Payne, R.J.,Riboldi-Tunnicliffe, A.,Abell, A.D.,Lapthorn, A.J.,Abell, C. (deposition date: 2006-03-31, release date: 2007-04-10, Last modification date: 2023-12-13)
Primary citationPayne, R.J.,Riboldi-Tunnicliffe, A.,Kerbarh, O.,Abell, A.D.,Lapthorn, A.J.,Abell, C.
Design, synthesis, and structural studies on potent biaryl inhibitors of type II dehydroquinases.
Chemmedchem, 2:1010-1013, 2007
Cited by
PubMed: 17487901
DOI: 10.1002/cmdc.200700062
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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