2CH5

Crystal structure of human N-acetylglucosamine kinase in complex with N-acetylglucosamine

2CH5 の概要

• エントリーDOI: 10.2210/pdb2ch5/pdb
• 関連するPDBエントリー: 2CH6
• 分子名称: NAGK PROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: transferase, n-acetylglucosamine, glcnac, sugar kinase, ribonuclease h fold, sugar kinase/hsp70/actin superfamily, domain rotation, open conformation, closed conformation, hypothetical protein
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 152505.41

構造登録者

Weihofen, W.A.,Berger, M.,Chen, H.,Saenger, W.,Hinderlich, S. (登録日: 2006-03-13, 公開日: 2006-09-18, 最終更新日: 2024-05-01)

• 主引用文献: Weihofen, W.A.,Berger, M.,Chen, H.,Saenger, W.,Hinderlich, S.; Structures of Human N-Acetylglucosamine Kinase in Two Complexes with N-Acetylglucosamine and with Adp/Glucose: Insights Into Substrate Specificity and Regulation.; J.Mol.Biol., 364:388-, 2006; PubMed: 17010375; DOI: 10.1016/J.JMB.2006.08.085

実験手法

X-RAY DIFFRACTION (1.9 Å)