2CD8
Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1)
Summary for 2CD8
Entry DOI | 10.2210/pdb2cd8/pdb |
Related | 2BVJ 2C6H 2C7X 2CA0 |
Descriptor | CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, ... (4 entities in total) |
Functional Keywords | oxidoreductase, cytochrome p450, pikc, yc-17, macrolide monooxygenase, antibiotic biosynthesis, heme, iron, metal-binding |
Biological source | STREPTOMYCES VENEZUELAE |
Total number of polymer chains | 2 |
Total formula weight | 98677.68 |
Authors | Yermalitskaya, L.I.,Kim, Y.,Sherman, D.H.,Waterman, M.R.,Podust, L.M. (deposition date: 2006-01-20, release date: 2007-02-20, Last modification date: 2023-12-13) |
Primary citation | Sherman, D.H.,Li, S.,Yermalitskaya, L.V.,Kim, Y.,Smith, J.A.,Waterman, M.R.,Podust, L.M. The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281:26289-, 2006 Cited by PubMed: 16825192DOI: 10.1074/JBC.M605478200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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