2CAR
Crystal Structure Of Human Inosine Triphosphatase
Summary for 2CAR
Entry DOI | 10.2210/pdb2car/pdb |
Descriptor | INOSINE TRIPHOSPHATE PYROPHOSPHATASE (2 entities in total) |
Functional Keywords | hydrolase, inosine triphosphate pyrophosphohydrolase, inosine triphosphatase deficiency, itp, imp, disease mutation, nucleotide metabolism |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 43225.51 |
Authors | Stenmark, P.,Kursula, P.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Hogbom, M.,Holmberg Schiavone, L.,Kotenyova, T.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Nordlund, P. (deposition date: 2005-12-22, release date: 2006-01-04, Last modification date: 2023-12-13) |
Primary citation | Stenmark, P.,Kursula, P.,Flodin, S.,Graslund, S.,Landry, R.,Nordlund, P.,Schuler, H. Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T. J.Biol.Chem., 282:3182-, 2007 Cited by PubMed: 17138556DOI: 10.1074/JBC.M609838200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.09 Å) |
Structure validation
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