2CAR

Crystal Structure Of Human Inosine Triphosphatase

2CAR の概要

• エントリーDOI: 10.2210/pdb2car/pdb
• 分子名称: INOSINE TRIPHOSPHATE PYROPHOSPHATASE (2 entities in total)
• 機能のキーワード: hydrolase, inosine triphosphate pyrophosphohydrolase, inosine triphosphatase deficiency, itp, imp, disease mutation, nucleotide metabolism
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43225.51

構造登録者

Stenmark, P.,Kursula, P.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Hogbom, M.,Holmberg Schiavone, L.,Kotenyova, T.,Nilsson-Ehle, P.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Nordlund, P. (登録日: 2005-12-22, 公開日: 2006-01-04, 最終更新日: 2023-12-13)

• 主引用文献: Stenmark, P.,Kursula, P.,Flodin, S.,Graslund, S.,Landry, R.,Nordlund, P.,Schuler, H.; Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.; J.Biol.Chem., 282:3182-, 2007; PubMed: 17138556; DOI: 10.1074/JBC.M609838200

実験手法

X-RAY DIFFRACTION (1.09 Å)