2C9B

Lumazine Synthase from Mycobacterium tuberculosus Bound to 3-(1,3,7- TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL)

Summary for 2C9B

Entry DOI	10.2210/pdb2c9b/pdb
Related	1W19 1W29 2C92 2C94 2C97 2C9D
Descriptor	6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE, 3-(1,3,7-TRIHYDRO-9-D-RIBITYL-2,6,8-PURINETRIONE-7-YL), POTASSIUM ION, ... (6 entities in total)
Functional Keywords	transferase, inhibitor binding
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	10
Total formula weight	168670.53
Authors	Morgunova, E.,Illarionov, B.,Jin, G.,Haase, I.,Fischer, M.,Cushman, M.,Bacher, A.,Ladenstein, R. (deposition date: 2005-12-09, release date: 2006-12-13, Last modification date: 2023-12-13)
Primary citation	Morgunova, E.,Illarionov, B.,Sambaiah, T.,Haase, I.,Bacher, A.,Cushman, M.,Fischer, M.,Ladenstein, R. Structural and Thermodynamic Insights Into the Binding Mode of Five Novel Inhibitors of Lumazine Synthase from Mycobacterium Tuberculosis. FEBS J., 273:4790-4804, 2006 Cited by PubMed: 16984393 DOI: 10.1111/J.1742-4658.2006.05481.X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation