2C7W

Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity

2C7W の概要

• エントリーDOI: 10.2210/pdb2c7w/pdb
• 分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• 機能のキーワード: vascular endothelial growth factor-b, angiogenesis, cysteine-knot motif, tyrosine kinase, ischemia, mitogen, glycoprotein, growth factor, heparin-binding
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted: P49765
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22432.27

構造登録者

Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R. (登録日: 2005-11-29, 公開日: 2007-01-30, 最終更新日: 2023-12-13)

• 主引用文献: Iyer, S.,Scotney, P.D.,Nash, A.D.,Acharya, K.R.; Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding; J.Mol.Biol., 359:76-, 2006; PubMed: 16616187; DOI: 10.1016/J.JMB.2006.03.002

実験手法

X-RAY DIFFRACTION (2.48 Å)