2C73
Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins
Summary for 2C73
Entry DOI | 10.2210/pdb2c73/pdb |
Related | 1GOS 1H8R 1OJ9 1OJA 1OJB 1OJC 1OJD 1S2Q 1S2Y 1S3B 1S3E 2BK3 2BK4 2BK5 2BYB 2C64 2C65 2C66 2C67 2C70 2C72 2C75 2C76 |
Descriptor | AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE, N-PROPARGYL-1(S)-AMINOINDAN, ... (4 entities in total) |
Functional Keywords | oxidoreductase, enantioselectivity, fad, flavin, flavoprotein, human monoamine oxidase, inhibitor binding, mitochondrion, rasagiline, transmembrane, parkinson, acetylation |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side: P27338 |
Total number of polymer chains | 2 |
Total formula weight | 119557.04 |
Authors | Li, M.,Binda, C.,Mattevi, A.,Edmondson, D.E. (deposition date: 2005-11-17, release date: 2006-04-19, Last modification date: 2023-12-13) |
Primary citation | Li, M.,Binda, C.,Mattevi, A.,Edmondson, D.E. Functional Role of the Aromatic Cage in Human Monoamine Oxidase B: Structures and Catalytic Properties of Tyr435 Mutant Proteins Biochemistry, 45:4775-, 2006 Cited by PubMed: 16605246DOI: 10.1021/BI051847G PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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