2C5B
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with 2'deoxy-5'deoxy-fluoroadenosine.
Summary for 2C5B
Entry DOI | 10.2210/pdb2c5b/pdb |
Related | 1RQP 1RQR 2C2W 2C4T 2C4U 2C5H 2CBX 2CC2 |
Descriptor | 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE, 5'-FLUORO-2',5'-DIDEOXYADENOSINE, ... (4 entities in total) |
Functional Keywords | transferase, fluorinase, 5'-fluorodeoxyadenosine synthase, fla, inhibitor, aza, streptomyces cattleya, sam analogue |
Biological source | STREPTOMYCES CATTLEYA |
Total number of polymer chains | 3 |
Total formula weight | 98411.80 |
Authors | McEwan, A.R.,Deng, H.,McGlinchey, R.P.,Robinson, D.A.,O'Hagan, D.,Naismith, J.H.,Spencer, J. (deposition date: 2005-10-26, release date: 2007-02-20, Last modification date: 2023-12-13) |
Primary citation | Cobb, S.L.,Deng, H.,Mcewan, A.R.,Naismith, J.H.,O'Hagan, D.,Robinson, D.A. Substrate Specificity in Enzymatic Fluorination. The Fluorinase from Streptomyces Cattleya Accepts 2'-Deoxyadenosine Substrates. Org.Biomol.Chem., 4:1458-, 2006 Cited by PubMed: 16604208DOI: 10.1039/B600574H PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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