2C43

STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE- PHOSPHOPANTETHEINYL TRANSFERASE IN COMPLEX WITH COENZYME A

Summary for 2C43

• Entry DOI: 10.2210/pdb2c43/pdb
• Related: 2BYD
• Descriptor: AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE, COENZYME A, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: transferase, fatty acid biosynthesis, coenzyme a
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 38265.60

Authors

Bunkoczi, G.,Wu, X.,Dubinina, E.,Johansson, C.,Smee, C.,Turnbull, A.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Oppermann, U. (deposition date: 2005-10-14, release date: 2005-10-24, Last modification date: 2023-12-13)

• Primary citation: Bunkoczi, G.,Pasta, S.,Joshi, A.,Wu, X.,Kavanagh, K.L.,Smith, S.,Oppermann, U.; Mechanism and substrate recognition of human holo ACP synthase.; Chem. Biol., 14:1243-1253, 2007; PubMed: 18022563; DOI: 10.1016/j.chembiol.2007.10.013

Experimental method

X-RAY DIFFRACTION (1.93 Å)