2C3P

CRYSTAL STRUCTURE OF THE FREE RADICAL INTERMEDIATE OF PYRUVATE:FERREDOXIN OXIDOREDUCTASE FROM Desulfovibrio africanus

Summary for 2C3P

• Entry DOI: 10.2210/pdb2c3p/pdb
• Related: 1B0P 1KEK 2C3M 2C3O 2C3U 2C3Y 2C42 2PDA
• Descriptor: PYRUVATE-FERREDOXIN OXIDOREDUCTASE, IRON/SULFUR CLUSTER, 1-(2-{(2S,4R,5R)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-[(1S)-1-CARBOXY-1-HYDROXYETHYL]-4-METHYL-1,3-THIAZOLIDIN-5-YL}ETHOXY)-1,1,3,3-TETRAHYDROXY-1LAMBDA~5~-DIPHOSPHOX-1-EN-2-IUM 3-OXIDE, ... (6 entities in total)
• Functional Keywords: oxidoreductase, 4fe-4s, iron, iron-sulfur, iron-sulfur cluster, pyruvate catabolism, tpp-dependent enzyme, metal-binding, electron transport
• Biological source: DESULFOVIBRIO AFRICANUS
• Total number of polymer chains: 2
• Total formula weight: 270679.22

Authors

Cavazza, C.,Contreras-Martel, C.,Pieulle, L.,Chabriere, E.,Hatchikian, E.C.,Fontecilla-Camps, J.C. (deposition date: 2005-10-11, release date: 2006-02-15, Last modification date: 2023-12-13)

• Primary citation: Cavazza, C.,Contreras-Martel, C.,Pieulle, L.,Chabriere, E.,Hatchikian, E.C.,Fontecilla-Camps, J.C.; Flexibility of Thiamine Diphosphate Revealed by Kinetic Crystallographic Studies of the Reaction of Pyruvate-Ferredoxin Oxidoreductase with Pyruvate.; Structure, 14:217-, 2006; PubMed: 16472741; DOI: 10.1016/J.STR.2005.10.013

Experimental method

X-RAY DIFFRACTION (2.33 Å)