2C05

Crystal Structures of Eosinophil-derived Neurotoxin in Complex with the Inhibitors 5'-ATP, Ap3A, Ap4A and Ap5A

2C05 の概要

• エントリーDOI: 10.2210/pdb2c05/pdb
• 関連するPDBエントリー: 1GQV 1HI2 1HI3 1HI4 1HI5 1K2A 2BEX 2BZZ 2C01 2C02
• 分子名称: NONSECRETORY RIBONUCLEASE, ACETIC ACID, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: endonuclease, eosinophil, hydrolase, nuclease, ribonuclease, rnase us, rnase-2, inhibitor, 5'-atp, ap3a, ap4a, ap5a, chemotaxis, glycoprotein, polymorphism, sensory transduction
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Lysosome (Probable): P10153
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16508.19

構造登録者

Baker, M.D.,Holloway, D.E.,Swaminathan, G.J.,Acharya, K.R. (登録日: 2005-08-25, 公開日: 2006-01-18, 最終更新日: 2023-12-13)

• 主引用文献: Baker, M.D.,Holloway, D.E.,Swaminathan, G.J.,Acharya, K.R.; Crystal Structures of Eosinophil-Derived Neurotoxin (Edn) in Complex with the Inhibitors 5'- ATP, Ap(3)A, Ap(4)A, and Ap(5)A.; Biochemistry, 45:416-, 2006; PubMed: 16401072; DOI: 10.1021/BI0518592

実験手法

X-RAY DIFFRACTION (1.86 Å)