2BZG

Crystal structure of thiopurine S-methyltransferase.

2BZG の概要

• エントリーDOI: 10.2210/pdb2bzg/pdb
• 分子名称: THIOPURINE S-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: methyltransferase, polymorphism, transferase, psi, protein structure initiative, structural genomics consortium (sgc)
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27454.09

構造登録者

Battaile, K.P.,Wu, H.,Zeng, H.,Loppnau, P.,Dong, A.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Plotnikov, A.N.,Structural Genomics Consortium (SGC) (登録日: 2005-08-17, 公開日: 2005-08-25, 最終更新日: 2019-05-15)

• 主引用文献: Wu, H.,Horton, J.R.,Battaile, K.P.,Allali-Hassani, A.,Martin, F.,Zeng, H.,Loppnau, P.,Vedadi, M.,Bochkarev, A.,Plotnikov, A.N.,Cheng, X.; Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase.; Proteins, 67:198-, 2007; PubMed: 17243178; DOI: 10.1002/PROT.21272

実験手法

X-RAY DIFFRACTION (1.58 Å)