2BZ9
Ligand-free structure of sterol 14alpha-demethylase from Mycobacterium tuberculosis in P2(1) space group
Summary for 2BZ9
Entry DOI | 10.2210/pdb2bz9/pdb |
Related | 1E9X 1EA1 1H5Z |
Descriptor | STEROL 14ALPHA-DEMETHYLASE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total) |
Functional Keywords | sterol 14alpha-demethylase, p450, electron transport, heme, iron, lipid synthesis, metal-binding, monooxygenase |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 2 |
Total formula weight | 104187.54 |
Authors | Yermalitskaya, L.V.,Waterman, M.R.,Podust, L.M. (deposition date: 2005-08-12, release date: 2006-12-07, Last modification date: 2023-12-13) |
Primary citation | Podust, L.M.,Von Kries, J.P.,Eddine, A.N.,Kim, Y.,Yermalitskaya, L.V.,Kuehne, R.,Ouellet, H.,Warrier, T.,Altekoster, M.,Lee, J.-S.,Rademann, J.,Oschkinat, H.,Kaufmann, S.H.E.,Waterman, M.R. Small Molecule Scaffolds for Cyp51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography Antimicrob.Agents Chemother., 51:3915-, 2007 Cited by PubMed: 17846131DOI: 10.1128/AAC.00311-07 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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