2BW0

Crystal Structure of the hydrolase domain of Human 10-Formyltetrahydrofolate 2 dehydrogenase

Summary for 2BW0

Entry DOI	10.2210/pdb2bw0/pdb
Descriptor	10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, SULFATE ION (3 entities in total)
Functional Keywords	dehydrogenase, nucleotide biosynthesis, oxidoreductase
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: O75891
Total number of polymer chains	1
Total formula weight	36671.68
Authors	Ogg, D.J.,Stenmark, P.,Arrowsmith, C.,Edwards, A.,Ehn, M.,Graslund, S.,Hammarstrom, M.,Hallberg, M.,Kotenyova, T.,Nilsson-Ehle, P.,Nordlund, P.,Persson, C.,Sagemark, J.,Schuler, H.,Sundstrom, M.,Thorsell, A.,Dobritzsch, D.,Weigelt, J. (deposition date: 2005-07-07, release date: 2005-07-08, Last modification date: 2023-12-13)
Primary citation	Kursula, P.,Schuler, H.,Flodin, S.,Nilsson-Ehle, P.,Ogg, D.J.,Savitsky, P.,Nordlund, P.,Stenmark, P. Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue. Acta Crystallogr.,Sect.D, 62:1294-, 2006 Cited by PubMed: 17057331 DOI: 10.1107/S0907444906026849 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation