2BUF

Arginine Feed-Back Inhibitable Acetylglutamate Kinase

Replaces:  1UVD

Summary for 2BUF

DescriptorACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMATE, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsacetyglutamate kinase, acetylglutamate, adp, arginine biosynthesis, feed-back inhibition, hexamer, transferase, arginine inhibition, allosteric mechanism, feedback control, amino acid kinase family
Biological sourcePSEUDOMONAS AERUGINOSA
Total number of polymer chains12
Total molecular weight387628.88
Authors
Ramon-Maiques, S.,Fernandez-Murga, M.L.,Vagin, A.,Fita, I.,Rubio, V. (deposition date: 2005-06-12, release date: 2005-12-13, Last modification date: 2019-05-08)
Primary citation
Ramon-Maiques, S.,Fernandez-Murga, M.L.,Gil-Ortiz, F.,Vagin, A.,Fita, I.,Rubio, V.
Structural Bases of Feed-Back Control of Arginine Biosynthesis, Revealed by the Structure of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga Maritima and Pseudomonas Aeruginosa
J.Mol.Biol., 356:695-, 2006
PubMed: 16376937 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2005.11.079
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.95 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers42 2.7% 13.7% 9.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2buf
no rotation
Molmil generated image of 2buf
rotated about x axis by 90°
Molmil generated image of 2buf
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2buf
no rotation
Molmil generated image of 2buf
rotated about x axis by 90°
Molmil generated image of 2buf
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2buf.pdb1.gz [270.81 KB])
Coordinate files for Biological unit (2buf.pdb2.gz [262.87 KB])