2BJC

NMR structure of a protein-DNA complex of an altered specificity mutant of the lac repressor headpiece that mimics the gal repressor

2BJC の概要

• エントリーDOI: 10.2210/pdb2bjc/pdb
• 関連するPDBエントリー: 1CJG 1EFA 1JWL 1JYE 1JYF 1L1M 1LBG 1LBH 1LBI 1LCC 1LCD 1LQC 1LTP 1OSL 1TLF
• NMR情報: BMRB: 7354
• 分子名称: LACTOSE OPERON REPRESSOR, 5'-D(*GP*AP*AP*TP*TP*GP*TP*AP*AP*GP *CP*GP*CP*TP*TP*AP*CP*AP*AP*TP*TP*C)-3' (2 entities in total)
• 機能のキーワード: transcription regulator, symmetric dna-binding, dna-binding, hth, lac operon, lac repressor, altered specificity, mutant, repressor, transcription regulation, transcription regulator/dna, gal repressor, gal operon, lac headpiece, symmetric dimer
• 由来する生物種: ESCHERICHIA COLI
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 26904.10

構造登録者

Salinas, R.K.,Folkers, G.E.,Bonvin, A.M.J.J.,Das, D.,Boelens, R.,Kaptein, R. (登録日: 2005-02-01, 公開日: 2005-10-18, 最終更新日: 2020-01-15)

• 主引用文献: Salinas, R.K.,Folkers, G.E.,Bonvin, A.M.J.J.,Das, D.,Boelens, R.,Kaptein, R.; Altered Specificity in DNA Binding by the Lac Repressor: A Mutant Lac Headpiece that Mimics the Gal Repressor; Chembiochem, 6:1628-, 2005; PubMed: 16094693; DOI: 10.1002/CBIC.200500049

実験手法

SOLUTION NMR