2BH2

Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine.

2BH2 の概要

• エントリーDOI: 10.2210/pdb2bh2/pdb
• 関連するPDBエントリー: 1UWV
• 分子名称: 23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, 23S RIBOSOMAL RNA 1932-1968, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
• 機能のキーワード: iron-sulfur cluster, methyltransferase, rna modification, rna processing, transferase, ruma, base flipping, sam, ob-fold, protein-rna complex, base stacking, substrate selectivity, general base, product release, 4fe-4s, metal-binding
• 由来する生物種: ESCHERICHIA COLI; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 121464.56

構造登録者

Lee, T.T.,Agarwalla, S.,Stroud, R.M. (登録日: 2005-01-06, 公開日: 2005-03-30, 最終更新日: 2023-12-13)

• 主引用文献: Lee, T.T.,Agarwalla, S.,Stroud, R.M.; A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function; Cell(Cambridge,Mass.), 120:599-, 2005; PubMed: 15766524; DOI: 10.1016/J.CELL.2004.12.037

実験手法

X-RAY DIFFRACTION (2.15 Å)