2BEG
3D Structure of Alzheimer's Abeta(1-42) fibrils
Summary for 2BEG
Entry DOI | 10.2210/pdb2beg/pdb |
Descriptor | Amyloid beta A4 protein (1 entity in total) |
Functional Keywords | alzheimer's, fibril, protofilament, beta-sandwich, quenched hydrogen/deuterium exchange, pairwise mutagenesis, protein fibril |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 5 |
Total formula weight | 22600.44 |
Authors | Luhrs, T.,Ritter, C.,Adrian, M.,Riek-Loher, D.,Bohrmann, B.,Dobeli, H.,Schubert, D.,Riek, R. (deposition date: 2005-10-24, release date: 2005-11-22, Last modification date: 2024-05-22) |
Primary citation | Luhrs, T.,Ritter, C.,Adrian, M.,Riek-Loher, D.,Bohrmann, B.,Dobeli, H.,Schubert, D.,Riek, R. 3D structure of Alzheimer's amyloid-{beta}(1-42) fibrils. Proc.Natl.Acad.Sci.Usa, 102:17342-17347, 2005 Cited by PubMed: 16293696DOI: 10.1073/pnas.0506723102 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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