2BEC

Crystal structure of CHP2 in complex with its binding region in NHE1 and insights into the mechanism of pH regulation

2BEC の概要

• エントリーDOI: 10.2210/pdb2bec/pdb
• 分子名称: Calcineurin B homologous protein 2, Sodium/hydrogen exchanger 1, YTTRIUM (III) ION (3 entities in total)
• 機能のキーワード: calcineurin-homologous protein, calcium-binding protein, nhe1 regulating protein, metal binding protein-transport protein complex, metal binding protein/transport protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein: P19634
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28509.78

構造登録者

Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S. (登録日: 2005-10-24, 公開日: 2006-06-27, 最終更新日: 2024-03-13)

• 主引用文献: Ben Ammar, Y.,Takeda, S.,Hisamitsu, T.,Mori, H.,Wakabayashi, S.; Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation; Embo J., 25:2315-2325, 2006; PubMed: 16710297; DOI: 10.1038/sj.emboj.7601145

実験手法

X-RAY DIFFRACTION (2.7 Å)