2BDM
Structure of Cytochrome P450 2B4 with Bound Bifonazole
Summary for 2BDM
Entry DOI | 10.2210/pdb2bdm/pdb |
Related | 1PO5 1SUO |
Descriptor | Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, ... (5 entities in total) |
Functional Keywords | p450, monooxygenase, oxidoreductase, membrane protein, cyp 2b4, cyp lm2 |
Biological source | Oryctolagus cuniculus (rabbit) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P00178 |
Total number of polymer chains | 1 |
Total formula weight | 57695.04 |
Authors | Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D. (deposition date: 2005-10-20, release date: 2005-12-27, Last modification date: 2023-08-23) |
Primary citation | Zhao, Y.,White, M.A.,Muralidhara, B.K.,Sun, L.,Halpert, J.R.,Stout, C.D. Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction. J.Biol.Chem., 281:5973-5981, 2006 Cited by PubMed: 16373351DOI: 10.1074/jbc.M511464200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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