2BCD
X-ray crystal structure of Protein Phosphatase-1 with the marine toxin motuporin bound
Summary for 2BCD
Entry DOI | 10.2210/pdb2bcd/pdb |
Related | 2BDX |
Related PRD ID | PRD_000213 |
Descriptor | Serine/threonine protein phosphatase PP1-gamma catalytic subunit, MOTUPORIN, BETA-MERCAPTOETHANOL, ... (5 entities in total) |
Functional Keywords | protein phosphtase, natural product inhibitors, motuporin, nodularin, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P36873 |
Total number of polymer chains | 2 |
Total formula weight | 38412.47 |
Authors | Maynes, J.T.,Luu, H.A.,Cherney, M.M.,Andersen, R.J.,Williams, D.,Holmes, C.F.,James, M.N. (deposition date: 2005-10-19, release date: 2006-01-17, Last modification date: 2023-11-15) |
Primary citation | Maynes, J.T.,Luu, H.A.,Cherney, M.M.,Andersen, R.J.,Williams, D.,Holmes, C.F.,James, M.N. Crystal Structures of Protein Phosphatase-1 Bound to Motuporin and Dihydromicrocystin-LA: Elucidation of the Mechanism of Enzyme Inhibition by Cyanobacterial Toxins. J.Mol.Biol., 356:111-120, 2006 Cited by PubMed: 16343532DOI: 10.1016/j.jmb.2005.11.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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