2BAL
p38alpha MAP kinase bound to pyrazoloamine
Summary for 2BAL
Entry DOI | 10.2210/pdb2bal/pdb |
Related | 2BAJ 2BAK 2BAQ |
Descriptor | Mitogen-activated protein kinase 14, [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE (3 entities in total) |
Functional Keywords | p38, map kinase, serine/threonine kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 42453.36 |
Authors | Gerhardt, S.,Pauptit, R.A.,Read, J.,Tucker, J.,Norman, R.A.,Breed, J. (deposition date: 2005-10-14, release date: 2005-12-06, Last modification date: 2011-07-13) |
Primary citation | Sullivan, J.E.,Holdgate, G.A.,Campbell, D.,Timms, D.,Gerhardt, S.,Breed, J.,Breeze, A.L.,Bermingham, A.,Pauptit, R.A.,Norman, R.A.,Embrey, K.J.,Read, J.,Vanscyoc, W.S.,Ward, W.H. Prevention of MKK6-Dependent Activation by Binding to p38alpha MAP Kinase. Biochemistry, 44:16475-16490, 2005 Cited by PubMed: 16342939DOI: 10.1021/bi051714v PDB entries with the same primary citation |
Experimental method |
Structure validation
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