2B4G

dihydroorotate dehydrogenase

2B4G の概要

• エントリーDOI: 10.2210/pdb2b4g/pdb
• 分子名称: dihydroorotate dehydrogenase, BROMIDE ION, FLAVIN MONONUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: structural genomics, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, oxidoreductase
• 由来する生物種: Trypanosoma brucei
• 細胞内の位置: Cytoplasm : Q57U83
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 141591.70

構造登録者

Arakaki, T.L.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (登録日: 2005-09-23, 公開日: 2005-10-11, 最終更新日: 2023-09-20)

• 主引用文献: Arakaki, T.L.,Buckner, F.S.,Gillespie, J.R.,Malmquist, N.A.,Phillips, M.A.,Kalyuzhniy, O.,Luft, J.R.,Detitta, G.T.,Verlinde, C.L.,Van Voorhis, W.C.,Hol, W.G.,Merritt, E.A.; Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies; Mol.Microbiol., 68:37-50, 2008; PubMed: 18312275; DOI: 10.1111/j.1365-2958.2008.06131.x

実験手法

X-RAY DIFFRACTION (1.95 Å)