2B4C

Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody

Summary for 2B4C

Entry DOI	10.2210/pdb2b4c/pdb
Descriptor	envelope glycoprotein, T-cell surface glycoprotein CD4, anti-HIV-1 gp120 immunoglobulin X5 light chain, ... (8 entities in total)
Functional Keywords	hiv-1, gp120, jrfl, v3, x5, cd4 induced antibody, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	4
Total formula weight	108808.79
Authors	Huang, C.,Tang, M.,Zhang, M.Y.,Majeed, S.,Montabana, E.,Stanfield, R.L.,Dimitrov, D.S.,Korber, B.,Sodroski, J.,Wilson, I.A.,Wyatt, R.,Kwong, P.D. (deposition date: 2005-09-23, release date: 2005-11-15, Last modification date: 2023-08-23)
Primary citation	Huang, C.C.,Tang, M.,Zhang, M.Y.,Majeed, S.,Montabana, E.,Stanfield, R.L.,Dimitrov, D.S.,Korber, B.,Sodroski, J.,Wilson, I.A.,Wyatt, R.,Kwong, P.D. Structure of a V3-containing HIV-1 gp120 core. Science, 310:1025-1028, 2005 Cited by PubMed: 16284180 DOI: 10.1126/science.1118398 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation