2B4C
Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | envelope glycoprotein | polymer | 344 | 38452.7 | 1 | GenBank (1465781) Pfam (PF00516) UniProt (by SIFTS) (Q75760) | Human immunodeficiency virus 1 | |
| 2 | B (C) | T-cell surface glycoprotein CD4 | polymer | 181 | 20129.9 | 1 | UniProt (P01730) Pfam (PF00047) Pfam (PF05790) | Homo sapiens (human) | T-cell surface antigen T4/Leu-3 |
| 3 | C (L) | anti-HIV-1 gp120 immunoglobulin X5 light chain | polymer | 215 | 23267.8 | 1 | Homo sapiens (human) | ||
| 4 | D (H) | anti-HIV-1 gp120 immunoglobulin X5 heavy chain | polymer | 235 | 24990.7 | 1 | Homo sapiens (human) | ||
| 5 | E (A) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 6 | F, G, H (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 7 | I, J, N, O, P (G, L, H) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 8 | K, L, M (H) | Xylitol | non-polymer | 152.1 | 3 | Chemie (XYL) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 106841.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1600.4 | |
| All* | Total formula weight | 108808.8 |
