2B17

Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Crystal structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution:

2B17 の概要

• エントリーDOI: 10.2210/pdb2b17/pdb
• 関連するPDBエントリー: 1Q7A
• 分子名称: Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ... (4 entities in total)
• 機能のキーワード: drugs, complex, inhibiton, hydrolase
• 由来する生物種: Daboia russellii pulchella
• 細胞内の位置: Secreted: P59071
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14118.04

構造登録者

Singh, N.,Jabeen, T.,Sharma, S.,Singh, T.P. (登録日: 2005-09-15, 公開日: 2005-10-04, 最終更新日: 2011-07-13)

• 主引用文献: Singh, N.,Jabeen, T.,Sharma, S.,Somvanshi, R.K.,Dey, S.,Srinivasan, A.,Singh, T.P.; Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.; Acta Crystallogr.,Sect.D, 62:410-416, 2006; PubMed: 16552142; DOI: 10.1107/S0907444906003660

実験手法

X-RAY DIFFRACTION (2.71 Å)