2ARF
Solution structure of the Wilson ATPase N-domain in the presence of ATP
Summary for 2ARF
Entry DOI | 10.2210/pdb2arf/pdb |
NMR Information | BMRB: 6914 |
Descriptor | WILSON DISEASE ATPASE (1 entity in total) |
Functional Keywords | atpase, wilson disease, p-type atpase, atp7b, copper transport, nucleotide binding, atp binding, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein (By similarity). Isoform 2: Cytoplasm. WND/140 kDa: Mitochondrion: P35670 |
Total number of polymer chains | 1 |
Total formula weight | 17309.91 |
Authors | Dmitriev, O.,Tsivkovskii, R.,Abildgaard, F.,Morgan, C.T.,Markley, J.L.,Lutsenko, S. (deposition date: 2005-08-19, release date: 2006-02-28, Last modification date: 2024-05-22) |
Primary citation | Dmitriev, O.,Tsivkovskii, R.,Abildgaard, F.,Morgan, C.T.,Markley, J.L.,Lutsenko, S. Solution structure of the N-domain of Wilson disease protein: Distinct nucleotide-binding environment and effects of disease mutations Proc.Natl.Acad.Sci.Usa, 103:5302-5307, 2006 Cited by PubMed: 16567646DOI: 10.1073/pnas.0507416103 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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