2AHR

Crystal Structures of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus pyogenes

Summary for 2AHR

• Entry DOI: 10.2210/pdb2ahr/pdb
• Related: 1YQG 2AG8
• Descriptor: putative pyrroline carboxylate reductase, SODIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: 1-pyrroline-5-carboxylate reductase, pyrroline-5-carboxylate reductase, pyrroline reductase, proline biosynthesis, nad(p)binding protein, rossmann fold, doain swapping, human pathogen, streptococcus pyogenes, structural genomics, mcsg, psi, protein structure initiative, midwest center for structural genomics, oxidoreductase
• Biological source: Streptococcus pyogenes
• Cellular location: Cytoplasm : Q9A1S9
• Total number of polymer chains: 5
• Total formula weight: 143728.36

Authors

Nocek, B.,Lezondra, L.,Holzle, D.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2005-07-28, release date: 2005-09-13, Last modification date: 2017-10-11)

• Primary citation: Nocek, B.,Chang, C.,Li, H.,Lezondra, L.,Holzle, D.,Collart, F.,Joachimiak, A.; Crystal Structures of Delta(1)-Pyrroline-5-carboxylate Reductase from Human Pathogens Neisseria meningitides and Streptococcus pyogenes; J.Mol.Biol., 354:91-106, 2005; PubMed: 16233902; DOI: 10.1016/j.jmb.2005.08.036

Experimental method

X-RAY DIFFRACTION (2.15 Å)