2AHM
Crystal structure of SARS-CoV super complex of non-structural proteins: the hexadecamer
2AHM の概要
エントリーDOI | 10.2210/pdb2ahm/pdb |
分子名称 | Replicase polyprotein 1ab, light chain, Replicase polyprotein 1ab, heavy chain, GLYCEROL, ... (5 entities in total) |
機能のキーワード | sars-cov, coronavirus, non-structural protein, nsp7, nsp8, super-complex, hexadecamer, viral protein, replication |
由来する生物種 | SARS coronavirus 詳細 |
細胞内の位置 | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 P59641 |
タンパク質・核酸の鎖数 | 8 |
化学式量合計 | 128507.40 |
構造登録者 | |
主引用文献 | Zhai, Y.J.,Sun, F.,Li, X.,Pang, H.,Xu, X.,Bartlam, M.,Rao, Z. Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer NAT.STRUCT.MOL.BIOL., 12:980-986, 2005 Cited by PubMed: 16228002DOI: 10.1038/nsmb999 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
構造検証レポート
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