2AH9

Crystal Structure of Human M340H-Beta-1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with Chitotriose

Summary for 2AH9

• Entry DOI: 10.2210/pdb2ah9/pdb
• Related: 1O0R 1TVY 1TW1 1TW5 2AE7 2AEC 2AES 2AGD
• Related PRD ID: PRD_900017
• Descriptor: Beta-1,4-galactosyltransferase 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE, ... (9 entities in total)
• Functional Keywords: beta1, 4-galactosyltransferase-i; trisaccharide; chitotriose; closed conformation; mutant, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 104430.40

Authors

Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K. (deposition date: 2005-07-27, release date: 2005-10-04, Last modification date: 2023-08-23)

• Primary citation: Ramasamy, V.,Ramakrishnan, B.,Boeggeman, E.,Ratner, D.M.,Seeberger, P.H.,Qasba, P.K.; Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety; J.Mol.Biol., 353:53-67, 2005; PubMed: 16157350; DOI: 10.1016/j.jmb.2005.07.050

Experimental method

X-RAY DIFFRACTION (2 Å)