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2ADF

Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain

Summary for 2ADF
Entry DOI10.2210/pdb2adf/pdb
DescriptorVon Willebrand factor, 82D6A3 IgG, ACETIC ACID, ... (7 entities in total)
Functional Keywordson willebrand factor, a3-domain, 82d6a3, collagen binding, paratope, epitope, antithrombotic, blood clotting-immune system complex, blood clotting/immune system
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P04275 P84751
Total number of polymer chains3
Total formula weight67880.02
Authors
Staelens, S.,Hadders, M.A.,Vauterin, S.,Platteau, C.,Vanhoorelbeke, K.,Huizinga, E.G.,Deckmyn, H. (deposition date: 2005-07-20, release date: 2005-12-06, Last modification date: 2023-10-25)
Primary citationStaelens, S.,Hadders, M.A.,Vauterin, S.,Platteau, C.,De Maeyer, M.,Vanhoorelbeke, K.,Huizinga, E.G.,Deckmyn, H.
Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
J.Biol.Chem., 281:2225-2231, 2006
Cited by
PubMed: 16314412
DOI: 10.1074/jbc.M508191200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

217705

数据于2024-03-27公开中

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