2ABL
SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE
Summary for 2ABL
Entry DOI | 10.2210/pdb2abl/pdb |
Descriptor | ABL TYROSINE KINASE (2 entities in total) |
Functional Keywords | transferase, tyrosine kinase, sh3, sh2, oncoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 1 |
Total formula weight | 18122.95 |
Authors | Nam, H.-J.,Frederick, C.A. (deposition date: 1996-11-17, release date: 1997-09-04, Last modification date: 2024-04-03) |
Primary citation | Nam, H.J.,Haser, W.G.,Roberts, T.M.,Frederick, C.A. Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism. Structure, 4:1105-1114, 1996 Cited by PubMed: 8805596DOI: 10.1016/S0969-2126(96)00116-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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