2ABL

SH3-SH2 DOMAIN FRAGMENT OF HUMAN BCR-ABL TYROSINE KINASE

Summary for 2ABL

Entry DOI	10.2210/pdb2abl/pdb
Descriptor	ABL TYROSINE KINASE (2 entities in total)
Functional Keywords	transferase, tyrosine kinase, sh3, sh2, oncoprotein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
Total number of polymer chains	1
Total formula weight	18122.95
Authors	Nam, H.-J.,Frederick, C.A. (deposition date: 1996-11-17, release date: 1997-09-04, Last modification date: 2024-04-03)
Primary citation	Nam, H.J.,Haser, W.G.,Roberts, T.M.,Frederick, C.A. Intramolecular interactions of the regulatory domains of the Bcr-Abl kinase reveal a novel control mechanism. Structure, 4:1105-1114, 1996 Cited by PubMed: 8805596 DOI: 10.1016/S0969-2126(96)00116-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation