2AAF

Structure of H278A arginine deiminase with L-arginine forming a S-alkylthiouronium reaction intermediate

Summary for 2AAF

Entry DOI	10.2210/pdb2aaf/pdb
Related	1RXX 2A9G 2ABR 2ACI
Descriptor	Arginine deiminase (2 entities in total)
Functional Keywords	arginine degradation pathway, l-arginine deiminase, catalytic mechanism, hydrolase
Biological source	Pseudomonas aeruginosa
Cellular location	Cytoplasm : P13981
Total number of polymer chains	4
Total formula weight	186328.00
Authors	Galkin, A.,Lu, X.,Dunaway-Mariano, D.,Herzberg, O. (deposition date: 2005-07-13, release date: 2005-08-09, Last modification date: 2023-08-23)
Primary citation	Galkin, A.,Lu, X.,Dunaway-Mariano, D.,Herzberg, O. Crystal Structures Representing the Michaelis Complex and the Thiouronium Reaction Intermediate of Pseudomonas aeruginosa Arginine Deiminase. J.Biol.Chem., 280:34080-34087, 2005 Cited by PubMed: 16091358 DOI: 10.1074/jbc.M505471200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation