2A72
Structure of the regulator of G-protein signaling domain of RGS7
Summary for 2A72
Entry DOI | 10.2210/pdb2a72/pdb |
Descriptor | Regulator of G-protein signalling 7, CHLORIDE ION (3 entities in total) |
Functional Keywords | human rgs7, regulator of g-protein signaling 7, gtpase-activating proteins (gap), structural genomics, structural genomics consortium, sgc, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol : P49802 |
Total number of polymer chains | 2 |
Total formula weight | 34312.20 |
Authors | Schoch, G.A.,Johansson, C.,Phillips, C.,Debreczeni, J.,Smee, C.,Elkins, J.M.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,von Delft, F.,Gileadi, O.,Doyle, D.A.,Structural Genomics Consortium (SGC) (deposition date: 2005-07-04, release date: 2005-07-12, Last modification date: 2024-04-03) |
Primary citation | Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P. Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008 Cited by PubMed: 18434541DOI: 10.1073/pnas.0801508105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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