2A72

Structure of the regulator of G-protein signaling domain of RGS7

2A72 の概要

• エントリーDOI: 10.2210/pdb2a72/pdb
• 分子名称: Regulator of G-protein signalling 7, CHLORIDE ION (3 entities in total)
• 機能のキーワード: human rgs7, regulator of g-protein signaling 7, gtpase-activating proteins (gap), structural genomics, structural genomics consortium, sgc, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, cytosol : P49802
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34312.20

構造登録者

Schoch, G.A.,Johansson, C.,Phillips, C.,Debreczeni, J.,Smee, C.,Elkins, J.M.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,von Delft, F.,Gileadi, O.,Doyle, D.A.,Structural Genomics Consortium (SGC) (登録日: 2005-07-04, 公開日: 2005-07-12, 最終更新日: 2024-04-03)

• 主引用文献: Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.; Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.; Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008; PubMed: 18434541; DOI: 10.1073/pnas.0801508105

実験手法

X-RAY DIFFRACTION (2 Å)