2A4W

Crystal Structure Of Mitomycin C-Binding Protein Complexed with Copper(II)-Bleomycin A2

Summary for 2A4W

• Entry DOI: 10.2210/pdb2a4w/pdb
• Descriptor: Mitomycin-Binding Protein, COPPER (II) ION, BLEOMYCIN A2, ... (4 entities in total)
• Functional Keywords: alfa/beta protein, mitomycin c-binding protein, copper(ii)-bleomycin a2, structural genomics, nppsfa, national project on protein structural and functional analyses, antimicrobial protein
• Biological source: Streptomyces caespitosus
• Total number of polymer chains: 2
• Total formula weight: 32412.67

Authors

Danshiitsoodol, N.,de Pinho, C.A.,Matoba, Y.,Kumagai, T.,Sugiyama, M. (deposition date: 2005-06-30, release date: 2006-07-18, Last modification date: 2023-10-25)

• Primary citation: Danshiitsoodol, N.,de Pinho, C.A.,Matoba, Y.,Kumagai, T.,Sugiyama, M.; The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein; J.Mol.Biol., 360:398-408, 2006; PubMed: 16756991; DOI: 10.1016/j.jmb.2006.05.017

Experimental method

X-RAY DIFFRACTION (1.5 Å)