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2A3C

Crystal structure of Aspergillus fumigatus chitinase B1 in complex with pentoxifylline

Summary for 2A3C
Entry DOI10.2210/pdb2a3c/pdb
Related1W9P 1W9U 1W9V 2A3A 2A3B 2A3E
Descriptorchitinase, SULFATE ION, 3,7-DIMETHYL-1-(5-OXOHEXYL)-3,7-DIHYDRO-1H-PURINE-2,6-DIONE, ... (4 entities in total)
Functional Keywords(beta-alpha)8 barrel, chitinase-pentoxifylline complex, hydrolase
Biological sourceAspergillus fumigatus
Cellular locationSecreted : Q873X9
Total number of polymer chains2
Total formula weight97109.34
Authors
Rao, F.V.,Andersen, O.A.,Vora, K.A.,DeMartino, J.A.,van Aalten, D.M.F. (deposition date: 2005-06-24, release date: 2005-09-27, Last modification date: 2023-10-25)
Primary citationRao, F.V.,Andersen, O.A.,Vora, K.A.,Demartino, J.A.,van Aalten, D.M.
Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes.
Chem.Biol., 12:973-980, 2005
Cited by
PubMed: 16183021
DOI: 10.1016/j.chembiol.2005.07.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.07 Å)
Structure validation

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